Innovative natural solutions for vaginal health

Vaginal discomfort can severely affect women’s quality of life through disabling symptoms such as itching, burning, smelly vaginal discharge, etc. Although triggers can vary, one of the most common is the use of antibiotics which induces a disruption of the vaginal microbiota composition, thus favoring the overgrowth of pathogens such as Candida albicans over Lactobacilli, which are the most prominent microorganisms in a healthy vaginal flora.

This unbalance creates suitable conditions for the development of a vaginal infection called vulvovaginal candidiasis. With over 75% of women worldwide experiencing at least one episode in their life, it is definitely the most prevalent vaginal condition affecting women in childbearing age.

For vaginal health, Lesaffre Human Care offers two distinct ingredients for day-to-day support to deliver long term result

  • Lynside® VAGINACTIV Oral: a unique probiotic yeast (Saccharomyces cerevisiae CNCM I-3856) designed for oral use;
  • Pharma VAGINACTIV Local: a specific dried yeast designed for medical devices for vaginal application and certified Active Pharmaceutical Ingredient (API). The study published in the journal Virulence1 also identified the benefits of Pharma VAGINACTIV Local on the course of vaginal candidiasis. The dried yeast was proven to:
    - Accelerate the pathogen clearance
    - Protect the vaginal epithelium
    - Improve vaginal candidiasis pharmaceutical treatment efficacy

    Pharma VAGINACTIV Local’s action is 100% mechanical and therefore suitable for medical devices according to new European regulation stating that no probiotic will be authorized in medical device formulation starting in 2020.

Offering different responses to a common challenge, these two ingredients can be used individually or concomitantly to fight vaginal infections and prevent recurrence.

1 Pericolini E, Gabrielli E, Ballet N, Sabbatini S, Roselletti E, Cayzeele Decherf A, Pélerin F, Luciano E, Perito S, Justen P, Vecchiarelli A.Therapeutic activity of a Saccharomyces cerevisiae-based probiotic and inactivated whole yeast on vaginal candidiasis. Virulence. 2016 Jul 19:0. DOI: 10.1080/21505594.2016.1213937